Halámková Lab
Dr. Lenka Halámková

Dr. Lenka Halámková

Assistant Professor
Department of Environmental Toxicology
Texas Tech University, Lubbock, TX

Welcome to our lab where we combine cutting-edge analytical chemistry with machine learning to solve real-world problems in forensic science, environmental toxicology, and public health.

Research Focus

Our lab sits at the intersection of analytical chemistry, data science, and real-world applications. We develop innovative methods that combine vibrational spectroscopy with machine learning to tackle challenges in forensic science, toxicology, and public health.

🔍 Forensic Drug Detection

Developing rapid, non-destructive methods to detect fentanyl and other dangerous substances in biological samples using advanced spectroscopic techniques.

🧠 Machine Learning Applications

Applying neural networks, random forests, and other ML algorithms to extract meaningful patterns from complex spectroscopic data.

📊 High-Dimensional Data Analysis

Developing statistical methods to handle complex, high-dimensional datasets common in biological and environmental research.

🦌 Wildlife Disease Diagnostics

Creating innovative diagnostic tools for chronic wasting disease in wildlife populations using Raman spectroscopy.

🧬 Enzyme Kinetics & Inhibition

Understanding molecular mechanisms of enzyme inhibition through combined spectroscopic and computational approaches.

🌿 Environmental Applications

Applying multivariate statistics to understand environmental toxicology and biological system responses.

Recent Breakthroughs

Our recent work has shown that machine learning can achieve over 90% accuracy in detecting fentanyl from human nail samples - potentially revolutionizing workplace drug testing. We've also developed methods that can diagnose chronic wasting disease in wildlife with 100% accuracy at the animal level, offering new hope for wildlife conservation efforts.

Lab Members

Abraham Olayeri
Abraham Olayeri
PhD Student
Salahuddin Majumder
Salahuddin Majumder
PhD Student
Research Environment

Our lab provides a collaborative environment where students gain hands-on experience with cutting-edge analytical instruments and develop skills in both experimental design and computational data analysis. Students work on projects that directly impact public health and safety while contributing to the scientific literature.

Recent Publications

From Spectra to Signatures: Detecting Fentanyl in Human Nails with ATR–FTIR and Machine Learning
Barney, A., Trojan, V., Hrib, R., Newland, A., Halámek, J., Halámková, L.
Sensors (2025), 25(1), 227
Attenuated total reflection Fourier transform infrared spectroscopy (ATR-FTIR) analysis of human nails: Implications for age determination in forensics
Mitu, B., Trojan, V., Hrib, R., Halámková, L.
Journal of Forensic Sciences (2025), 70: 150-160
Phenotypic profiling based on body fluid traces discovered at the scene of crime: Raman spectroscopy of urine stains for race differentiation
Vyas, B., Halámková, L., Lednev, I. K.
Analyst (2024), 149, 20: 5081-5090
Evaluation of Fentanyl Exposure Effects on Butyrylcholinesterase Activity as a Tool for Future On-Site Detection Methods
Rania, V., Newland, A., Halámková, L., Trojan, V., Hřib, R., Halámek, J.
ACS Omega (2024), 9, 38, 40234-40241
Sex Determination of Human Nails Based on Attenuated Total Reflection Fourier Transform Infrared Spectroscopy in Forensic Context
Mitu, B., Trojan, V., Halámková, L.
Sensors (2023), 23, 9412
Attenuated Total Reflection Fourier Transform Infrared (ATR FT-IR) spectroscopy For Forensic Screening of Long-Term Alcohol Consumption from Human Nails
Mitu, B., Cerda, M., Hrib, R, Trojan, V., Halámková, L.
ACS Omega (2023), 8, 24, 22203–22210

You can find complete publication list here: https://scholar.google.com/citations?user=KoHhK4QAAAAJ&hl=en.

Laboratory Equipment

DXR3 Raman Microscope

DXR3™ Raman Microscope

Next-generation Thermo Fisher Scientific DXR3™ Raman Microscope for investigating chemical and molecular properties of materials. Features real-time preview, automated fluorescence correction, autoexposure, and cosmic ray rejection. Essential for analyzing evidence such as fibers, paints, drugs, and crime scene materials.

FTIR Spectrometer

Thermo Scientific™ Nicolet™ iS20 FTIR Spectrometer

Advanced FTIR spectroscopy system for identifying organic, polymeric, and inorganic materials. Uses infrared light to observe chemical characteristics, creating molecular fingerprints unique to each sample. Critical for forensic analysis and material identification.

Analytical Capabilities

Our state-of-the-art equipment allows us to perform non-destructive analysis of a wide range of samples, from biological tissues to forensic evidence. The combination of Raman and FTIR spectroscopy provides complementary information about molecular structure and composition, enabling comprehensive characterization of complex samples.

Teaching

ENTX 6300

Advanced Topics in Environmental Toxicology: Applied Multivariate Statistics & Machine Learning

Advanced graduate course covering cutting-edge statistical methods and machine learning applications in environmental toxicology. Students learn to handle high-dimensional data and apply modern computational approaches to real-world problems.

ENTX 6100

Stats Lab

Practical application of statistical methods to environmental data. Covers experimental design, hypothesis testing, regression analysis, and data visualization techniques essential for environmental research.

Teaching Philosophy

I believe in hands-on learning where students work with real datasets and learn to apply statistical methods to solve actual research problems. My courses emphasize both theoretical understanding and practical skills, preparing students to use advanced analytical methods in their own research.

Mountain Adventures

When I'm not in the lab analyzing data, you'll find me exploring mountains or running long distances on trails, or riding a bike, or just hanging out somewhere outdoors.

Austrian Alps - Ennstal & Gesäuse National Park

The Ennstal Alps and Gesäuse National Park offer some of the most spectacular alpine hiking I've experienced.

Sandia Mountains, New Mexico - Desert High Country

The Sandia Mountains via South Crest Trail and La Luz Trail.

The Rock The Ridge 50-mile race in the Catskill Mountains

The event supports the Mohonk Preserve, a nature conservation area protecting over 8,000 acres of land.

Dog Canyon Campground - Desert Wilderness

Dog Canyon : The Marcus, Blue Ridge and Bush Mt. trail (17 miles), Indian Meadow Natural Trail, and Lost Peak.

Wheeler Mt. - My first 4000-meters climb

Mt Wheeler, NM : the highest natural point in the U.S. state of New Mexico.

Outdoor Philosophy

"Never are my senses more engaged than when the pain sets in. There is a magic in misery. Just ask any runner." Dean Karnazes; ultramarathon runner

Contact Information

Email: Lenka.Halamkova@ttu.edu

Department of Environmental Toxicology

Texas Tech University, Lubbock, TX